It’s not often that a coming-of-age story revolves around a 29-year-old chronic masturbator who still lives with his mom, but that’s just one example of the many ways Daisuke Miura's Boys on the Run is refreshingly atypical. The film is based on a manga by Kengo Hanazawa which was originally serialized in Shogakukan’s Big Comic Spirits from 2005-2008, and although the adaptation is fairly loyal visually, the overall tone has been changed both in how the characters behave and how the story arc is presented.
When Jessy burns down his adoptive parents garage he is put into a youth prison. There he meets Roark another troublemake with whom he escapes and ends up in deserted woodlands. On their way they meet Rain, a girl that flees from her militia-captain Father. Together and with the Militia on their trail they try to escape in the hope of finding somewhere to make a new start of their lives.